A collection of talks from creative individuals striving to bring light to some of the world's most pressing issues.

Bonnie Bassler studies how bacteria can communicate with one another, through chemical signals, to act as a unit. Her work could pave the way for new, more potent medicine.

Cheryl Hayashi studies the delicate but terrifically strong silk threads that make up a spider's web, finding startling applications for human use.

Paul Rothemund folds DNA into shapes and patterns. Which is a simple enough thing to say, but the process he has developed has vast implications for computing and manufacturing -- allowing us to create things we can now only dream of.

Jack Horner and his dig teams have discovered the first evidence of parental care in dinosaurs, extensive nesting grounds, evidence of dinosaur herds, and the world’s first dinosaur embryos. He's now exploring how to build a dinosaur.

Inventor Saul Griffith looks for elegant ways to make real things, from low-cost eyeglasses to a kite that tows boats. His latest projects include open-source inventions and elegant new ways to generate power.

Edith Widder combines her expertise in research and technological innovation with a commitment to stopping and reversing the degradation of our marine environment.

Jacqueline Woodson writes books to be savored. She is best known for her memoir "Brown Girl Dreaming" along with her works "After Tupac and D Foster," "Feathers" and "Show Way." Her accolades include the MacArthur "Genius Grant" and the National Book Award. In this excerpt of a conversation she had with Debbie Millman on the podcast Design Matte...

Legendary skeptic James Randi devoted his life to debunking frauds and investigating paranormal and pseudoscientific claims.

Joe DeRisi hunts for the genes that make us sick. At his lab, he works to understand the genome of Plasmodium falciparum, the deadliest form of malaria.

In an emotionally charged talk, MacArthur-winning activist Majora Carter details her fight for environmental justice in the South Bronx -- and shows how minority neighborhoods suffer most from flawed urban policy.

Titus Kaphar's artworks interact with the history of art by appropriating its styles and mediums.

Mark Roth's research has reawakened an unusual notion from the annals of science: reversible metabolic hibernation. Yes, putting living organisms into suspended animation -- and bringing them back safely.

Sendhil Mullainathan asks a compelling question: what are the irrational choices we make that perpetuate poverty, corruption, discrimination?

Quite simply, Michael Moschen has revolutionized juggling, refining it into an art and a bit of a science. With a few flying balls and well-chosen props he will completely re-wire your notions of the physically possible.

Edwidge Danticat’s novels and short stories are fast becoming iconic representations of the immigrant experience -- and what it means to be Haitian-American.

Amy Smith designs cheap, practical fixes for tough problems in developing countries. Among her many accomplishments, the MIT engineer received a MacArthur "genius" grant in 2004 and was the first woman to win the Lemelson-MIT Prize for turning her ideas into inventions.

Barbara Block studies how tuna, billfish and sharks move around (and stay warm) in the open ocean. Knowing how these large predators travel through pelagic waters will help us understand their role in the wider ocean ecosystem.

As the CEO of MIT-inspired WiTricity, Eric Giler has a plan to beam electric power through the air to wirelessly power your laptop or recharge your car. You may never plug in again.

Andrea Ghez is a stargazing detective, tracking the visible and invisible forces lurking in the vastness of interstellar space.

Sara Seager’s research led to the first discovery of an atmosphere on a planet outside our solar system. Now she’s on the hunt for a twin Earth.

As a Pittsburgh youth besieged by racism in the crumbling remains of the steel economy, Bill Strickland should have been one of the Rust Belt's casualties. Instead, he discovered the potter's wheel, and the transforming power of fountains, irrepressible dreams, and the slide show.

Emma Belcher develops and implements strategy for reducing the threat posed by nuclear weapons.

Bob Stein has long been in the vanguard: immersed in radical politics as a young man, he grew into one of the founding fathers of new media. He’s wondering what sorts of new rituals and traditions might emerge as society expands to include increasing numbers of people in their eighties and nineties.

Heather Lanier illuminates truths about the human condition that speak to both the head and the heart.

The MacArthur Foundation revealed its list of 2015 Fellows this morning. Twenty-four people received the “genius grant,” a $625,000 no-strings-attached stipend -- and two of them are TED Fellows: Patrick Awuah and LaToya Ruby Frazier. Patrick Awuah founded Ashesi University, a college in his home country of Ghana dedicated to educating Af...

Jim Yong Kim is leading a global effort to end extreme poverty and promote shared prosperity.

Anna Deavere Smith's ground-breaking solo shows blur the lines between theater and journalism, using text from real-life encounters to create gripping portraits.

LaToya Ruby Frazier focuses her camera lens on working class families, exploring themes of family, inequality, health care and environmental racism.

Anne Basting is infusing the arts and humanities into the lives and care settings of uncommunicative patients.