Patricia Burchat studies the universe's most basic ingredients -- the mysterious dark energy and dark matter that are massively more abundant than the visible stars and galaxies. She is one of the founders of the BaBar Collaboration at the Stanford Linear Accelerator Center, a project that's hoping to answer the question, "If there are as many anti-particles as there are particles, why can't we see all these anti-particles?"

She's a member of the Large Synoptic Survey Telescope project, which will allow scientists to monitor exploding supernovae and determine how fast the universe is expanding -- and map how mass is distributed throughout the universe. She's also part of Fermilab Experiment E791, studying the production and decay of charmed particles. Burchat received a Guggenheim Fellowship in 2005.