Aparna Nancherla started out doing comedy in her hometown of Washington DC and now resides in New York City. She is a series regular in Comedy Central's Corporate and has reprised her role in season three of HBO's CRASHING.

Nancherla is also featured in the second season of Netflix's The Standups. Other television credits include Apple TV+'s Mythic Quest: Raven’s Banquet, Netflix's Master of None and LOVE, HBO's High Maintenance, Comedy Central's Inside Amy Schumer, appearing as a US correspondent for Dave's (UK) Unspun with Matt Forde and Hulu's I Love You, America with Sarah Silverman.

In 2018, Nancherla made her feature debut in the Paul Feig movie A Simple Favor. Her TV stand-up appearances include Seeso's stand-up series Night Train with Wyatt Cenac, season two of Comedy Central's Meltdown as well as Adam Devine's House Party. In 2013, she made her late night stand-up debut on TBS's Conan and was one of the breakout New Faces at the prestigious Just For Laughs Festival in Montreal. Her TV writing credits include Late Night with Seth Meyers as well as being a regular correspondent and writer on FX's Totally Biased with W. Kamau Bell.