How this disease changes the shape of your cells

What shape are your cells? Squishy cylinders? Jagged zig-zags? You might not spend a lot of time thinking about the bodies of these building blocks, but microscopically, small variations can have huge consequences. And while some adaptations change these shapes for the better, others can spark debilitating complications. Amber M. Yates dives into the science of the malignant sickle-cell mutation. [Directed by Axon Animation LLC, narrated by Susan Zimmerman, music by Stephen LaRosa].