Pastor Rick Warren is the author of The Purpose-Driven Life, which has sold more than 30 million copies worldwide. His has become an immensely influential voice seeking to apply the values of his faith to issues such as global poverty, HIV/AIDS and injustice.

Jim Yong Kim is leading a global effort to end extreme poverty and promote shared prosperity.

On a mission to create a hunger-free world, agricultural entrepreneur Cedric Habiyaremye makes the case for cultivating quinoa -- and other versatile, nutrient-rich grains -- in places experiencing malnutrition, like his native Rwanda. He shares a model to help smallholder farmers across Africa diversify their fields with nutritious and indigeno...

John Doerr is an engineer, acclaimed venture capitalist and the chairman of Kleiner Perkins.

Educating the poor is more than just a numbers game, says Shukla Bose. She tells the story of her groundbreaking Parikrma Humanity Foundation, which brings hope to India's slums by looking past the daunting statistics and focusing on treating each child as an individual.

We're at a unique moment in history, says UK Prime Minister Gordon Brown: we can use today's interconnectedness to develop our shared global ethic -- and work together to confront the challenges of poverty, security, climate change and the economy.

Philosopher Thomas Pogge wants to ensure medications get to those who need it most. He has published on a wide range of subjects such as global justice and human rights.

Solar-powered LED lightbulbs could transform the lives of rural Haitians, but as Daniel Schnitzer found, they don't simply sell themselves. At TEDxPittsburgh, he shows how smart health and energy products for the developing world are useless unless the market works too.

Sunitha Krishnan has dedicated her life to rescuing women and children from sex slavery, a multimilion-dollar global market. In this courageous talk, she tells three powerful stories, as well as her own, and calls for a more humane approach to helping these young victims rebuild their lives.

Abigail Disney advocates for real changes to the way capitalism operates in today's world.

For the poor and vulnerable, the health impacts of climate change are already here, says physician Cheryl Holder. Unseasonably hot temperatures, disease-carrying mosquitoes and climate gentrification threaten those with existing health conditions, while wealthier people move to higher ground. In an impassioned talk, Holder proposes impactful way...

Musician and activist Bono accepts the 2005 TED Prize with a riveting talk, arguing that aid to Africa isn't just another celebrity cause; it's a global emergency.