Science is a learning process that involves experimentation, failure and revision -- and the science of medicine is no exception. Cancer researcher Kevin B. Jones faces the deep unknowns about surgery and medical care with a simple answer: honesty. In a thoughtful talk about the nature of knowledge, Jones shows how science is at its best when sc...

Backed by stunning illustrations, David Christian narrates a complete history of the universe, from the Big Bang to the Internet, in a riveting 18 minutes. This is "Big History": an enlightening, wide-angle look at complexity, life and humanity, set against our slim share of the cosmic timeline.

When will the coronavirus vaccine be ready? Epidemiologist Seth Berkley (head of Gavi, the Vaccine Alliance) takes us inside the effort to create a vaccine for COVID-19. With clarity and urgency, he explains what makes it so challenging to develop, when we can expect it to be rolled out at scale and why we'll need global collaboration to get it ...

Over the past few centuries, Western cultures have been very good at creating general prosperity for themselves. Historian Niall Ferguson asks: Why the West, and less so the rest? He suggests half a dozen big ideas from Western culture -- call them the 6 killer apps -- that promote wealth, stability and innovation. And in this new century, he sa...

In this new season of The TED Interview, conversations with people who make a case for ... optimism. Not some blind, hopeful feeling, but the conviction that somewhere out there are solutions that, given the right attention and resources, can guide us out of the dark place we're in. For the first episode: artificial intelligence. Will innovation...

Our leaders need to be held accountable, says journalist Heather Brooke. And she should know: Brooke uncovered the British Parliamentary financial expenses that led to a major political scandal in 2009. She urges us to ask our leaders questions through platforms like Freedom of Information requests -- and to finally get some answers.

Even as the Deepwater Horizon tragedy unfolded, Carl Safina took the stage at TEDxOilSpill to share what the facts were known at the time. In a blood-boiling cross-examination, he suggests that the consequences will stretch far beyond the Gulf -- and many so-called solutions are making the situation worse.

Technologist and futurist Bill Joy talks about several big worries for humanity -- and several big hopes in the fields of health, education and future tech.