Christopher McDougall explores the mysteries of the human desire to run. How did running help early humans survive -- and what urges from our ancient ancestors spur us on today? McDougall tells the story of the marathoner with a heart of gold, the unlikely ultra-runner, and the hidden tribe in Mexico that runs to live.

Eva Vertes -- only 19 when she gave this talk -- discusses her journey toward studying medicine and her drive to understand the roots of cancer and Alzheimer’s.

We have lots in common with our closest primate relatives. But comparatively, humans seem a bit... underdressed. Instead of thick fur covering our bodies, many of us mainly have hair on top of our heads— and a few other places. So, how did we get so naked? And why do we have hair where we do? Nina G. Jablonski explores the evolution of human hai...

Anthony Atala's state-of-the-art lab grows human organs -- from muscles to blood vessels to bladders, and more. At TEDMED, he shows footage of his bio-engineers working with some of its sci-fi gizmos, including an oven-like bioreactor (preheat to 98.6 F) and a machine that "prints" human tissue.

Pioneering surgeon Susan Lim performed the first liver transplant in Asia. But a moral concern with transplants (where do donor livers come from ...) led her to look further, and to ask: Could we be transplanting cells, not whole organs? At the INK Conference, she talks through her new research, discovering healing cells in some surprising places.

Less than an hour after scrambling out the back door of the Columbine High School library on April 20, 1999, Austin Eubanks was lying in a hospital bed, medicated on a variety of painkillers. That was the beginning of a decade-long addiction that led to a profound realization about the current opioid epidemic: how we manage pain is both the prob...

Does the key to stopping cancer lie in the heart? Cardiologist Nicholas Leeper digs into emerging scientific research on the link between the world's two leading causes of death, heart disease and cancer, sharing how their biological origins may be connected -- and treatable with the same therapeutics. A call to challenge dogma and break down tr...

DNA isn't the only builder in the biological world -- there's also a mysterious bioelectric layer directing cells to work together to grow organs, systems and bodies, says biologist Michael Levin. Sharing unforgettable and groundbreaking footage of two-headed worms, he introduces us to xenobots -- the world's first living robots, created in his ...

Medical scans can produce thousands of images for a single patient in seconds, but how do doctors know what's useful? Scientific visualization expert Anders Ynnerman shows us sophisticated new tools -- like virtual autopsies -- for analyzing our data, and hints at the sci-fi-sounding medical technologies coming up next. This talk contains some g...

Instead of a boring slide deck at your next presentation, how about bringing in a troupe of dancers? That's science writer John Bohannon's "modest proposal" in this spellbinding choreographed talk. He makes his case by example, in collaboration with dancers from Black Label Movement.

(NOTE: This talk was given in 2010, and this field of science has developed quickly since then. Enjoy it as a piece of science history but not as the last word on this topic. Read "Criticisms & updates" below for more details.) William Li presents a new way to think about treating cancer and other diseases: anti-angiogenesis, preventing the ...

At some point in our lives, almost every one of us will have our heart broken. Imagine how different things would be if we paid more attention to this unique emotional pain. Psychologist Guy Winch reveals how recovering from heartbreak starts with a determination to fight our instincts to idealize and search for answers that aren't there -- and ...

"Bonk" author Mary Roach delves into obscure scientific research, some of it centuries old, to make 10 surprising claims about sexual climax, ranging from the bizarre to the hilarious. (This talk is aimed at adults. Viewer discretion advised.)

Louise Leakey asks, "Who are we?" The question takes her to the Rift Valley in Eastern Africa, where she digs for the evolutionary origins of humankind -- and suggests a stunning new vision of our competing ancestors.

Humorist John Hodgman rambles through a new story about aliens, physics, time, space and the way all of these somehow contribute to a sweet, perfect memory of falling in love.

Hugh Herr is building the next generation of bionic limbs, robotic prosthetics inspired by nature's own designs. Herr lost both legs in a climbing accident 30 years ago; now, as the head of the MIT Media Lab's Biomechatronics group, he shows his incredible technology in a talk that's both technical and deeply personal — with the help of ballroom...

When faced with life's toughest circumstances, how should we respond: as an optimist, a realist or something else? In an unforgettable talk, explorer Mark Pollock and human rights lawyer Simone George explore the tension between acceptance and hope in times of grief -- and share the groundbreaking work they're undertaking to cure paralysis.

When Joshua Prager was 19, a devastating bus accident left him a hemiplegic. He returned to Israel twenty years later to find the driver who turned his world upside down. In this mesmerizing tale of their meeting, Prager probes deep questions of nature, nurture, self-deception and identity.

The gastric brooding frog lays its eggs just like any other frog -- then swallows them whole to incubate. That is, it did until it went extinct 30 years ago. Paleontologist Michael Archer makes a case to bring back the gastric brooding frog and the thylacine, commonly known as the Tasmanian tiger.