Amy C. Edmondson studies people and teams seeking to make a positive difference through the work they do.

Robert Reffkin is on a mission to help everyone find their place in the world.

Writer, comic and mental health activist Kevin Breel speaks up about depression.

Clay Shirky argues that the history of the modern world could be rendered as the history of ways of arguing, where changes in media change what sort of arguments are possible -- with deep social and political implications.

Georgette Mulheir is a pioneer for the movement to end child abuse in the form of orphanages.

UNICEF executive director Henrietta Fore is a champion of economic development, education, health and humanitarian assistance.

Gabby Rivera is a Bronx-born, queer Latinx writer.

Mark Kendall aims to shake up how vaccines are delivered with the Nanopatch.

Asmeret Asefaw Berhe is a soil and global-change scientist and educator passionate about all things related to the science and beauty of soils.

Naoko Ishii leads the Global Environment Facility (GEF), a public financial institution that provides around US$1 billion every year to help tackle our planet’s most pressing environmental problems.

Researcher Johnny Lee became a YouTube star with his demo of Wii Remote hacks -- bending the low-cost game piece to power an interactive whiteboard, a multitouch surface, a head-mounted display ...

A record-breaker at the Paralympic Games in 1996, Aimee Mullins has built a career as a model, actor and advocate for women, sports and the next generation of prosthetics.

Working at the frontiers of interactive technology, Chris Milk stretches virtual reality into a new canvas for storytelling.

Dr. Brené Brown studies courage, vulnerability, shame and empathy.

Ernest Madu founded the Heart Institute of the Caribbean, a revolutionary clinic for cardiovascular diseases in Kingston, Jamaica -- revolutionary for offering first-class health care in a developing nation. His next stop: Nigeria.

Shekhar Kapur is a visionary filmmaker and storyteller who works at the intersection of art, myth and activism.

After creating and conducting a worldwide virtual choir on YouTube, Eric Whitacre is now touring with an astonishing live choir.

Harvard Medical School psychologist Susan David studies emotional agility: the psychology of how we can use emotion to bring forward our best selves in all aspects of how we love, live, parent and lead.

About this event: 100,000:1 The approximate ratio of Manx Residents to the World. Do we have something to offer to the rest of the human race? You bet! Come one, come all...in celebration of the Year of Culture, the Isle of Man's first (and by no means last!) TEDx event: TEDxDouglas...bringing together talented souls from on and off the Island to blow your mind...

About this event: What will the humans be like in 100 years to go? We are only separated by 4 generations and people of 2112 are our grandchildren. Is it possible that your granddaughter is a robot? You shouldn't deny the thought at once, as in 2012 a Japanese engineer created a robot-copy of himself. Technology is changing permanently and it is hard to predict h...

In her warm, glorious voice, Eddi Reader sings thoughtful songs about love, longing and introspection.

Chuck Nice is a radio and TV veteran with a passion for science communication and comedy.

Dan Berkenstock and his team at Skybox Imaging are rethinking how to take photographs from space.

Alex Laskey helps power companies to help their customers cut down -- using data analysis, marketing and a pinch of psychology.

Fabien Cousteau spent 31 days underwater to research how climate change and pollution are affecting the oceans.

When a freak tornado hit her Massachusetts hometown, Caitria O’Neill wasn't an expert in disaster relief recovery. But she learned quickly and is now passing her knowledge on through the website Recovers.org.

Rebeca Hwang is co-founder and managing director of Rivet Ventures, investing in solutions for women and empowering their choices.

About this event:

Susan Solomon enables support for human stem cell research, aiming to cure major diseases and empower more personalized medicine.

Zachariah Mampilly is an expert on the politics of both violent and non-violent resistance.