How can mothers with HIV avoid passing it to their kids? In South Africa, Mitchell Besser tapped a new resource for healthcare: moms themselves. The program he started, mothers2mothers, trains new mothers to educate and support other moms.
Danish political scientist Bjorn Lomborg heads the Copenhagen Consensus, which has prioritized the world's greatest problems -- global warming, world poverty, disease -- based on how effective our solutions might be. It's a thought-provoking, even provocative list.
Ernest Madu founded the Heart Institute of the Caribbean, a revolutionary clinic for cardiovascular diseases in Kingston, Jamaica -- revolutionary for offering first-class health care in a developing nation. His next stop: Nigeria.
Through his William J. Clinton Foundation, former US President Bill Clinton has become a vital and innovative force for world change. He works in four critical areas: health, economic empowerment, citizen service, and reconciliation.
Kristen Ashburn's photographs bring us face-to-face with real people in desperate circumstances. Taking us to the intimate spaces of her subjects -- the victims of war, disaster, epidemic -- she elicits the sublime sadness and resolve of human beings in suffering.
Pastor Rick Warren is the author of The Purpose-Driven Life, which has sold more than 30 million copies worldwide. His has become an immensely influential voice seeking to apply the values of his faith to issues such as global poverty, HIV/AIDS and injustice.
Bono, the lead singer of U2, uses his celebrity to fight for social justice worldwide: to end hunger, poverty and disease, especially in Africa. His nonprofit ONE raises awareness via media, policy and calls to action.
Noreena Hertz looks at global culture -- financial and otherwise -- using an approach that combines traditional economic analysis with foreign policy trends, psychology, behavioural economics, anthropology, history and sociology.