During TEDxChange "The Big Picture" we'll explore the following: In the current economic climate, our focus has shifted to needs closest to home. But still too many in our global, interdependent community cannot meet their most basic needs: food, clean water, life-saving medicines. We cannot proceed with business as usual. At TEDxChange, we’ll take a step back and look at the big picture: Why should we continue to invest in global health and development? And how can we work across borders and boundaries to make positive change? -- TEDxChange 2012 is a TEDx event co-organized by the Bill & Melinda Gates Foundation and TED. Convened by Melinda French Gates and hosted by Chris Anderson, TEDxChange will focus on issues surrounding global health and development. TEDxChange type events are TEDx events hosted around the live webcast of TEDxChange, and also feature local speakers. Our event is called TEDxSanJoaquinChange, and is one of many TEDx events happening around the globe on April 5th that will expand on the ideas brought up at TEDxChange 2010.