Problems are everyday more complex and require a real collaborative work to get solved. The Design Department at Universidad Iberoamericana has been encouraging out of the box thinking providing new learning models for innovation processes. Design represents a viable way in which NGO´s and companies can innovate and compete in the local scene. Focused on discovering the particular needs and desires of costumers and the possibilities of production and commercialization of organizations, designers can define, prospect and develop better products and services. During this TEDx event our students and alumni from Graphic, Industrial, Textile and Interactive Design will present new business, product or service ideas, conceived through user centered research and design thinking, around different local problems for which they have developed holistic and strategic design solutions.