Medical student at Queens University in Belfast, Ireland. Originally from San Diego where I surfed and ate burritos aplenty.
Medicine, biology, cosmology, astrology, evolutionary biology, kinesiology, neurology, philosophy, poetry, prose, technology, genetics, therapeutics, and innovation.
Explore. Dream. Discover.
I'm the annoying guy who incessantly posts TED lectures on Facebook...sometimes more than once per day.
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A comment on Talk: Mark Shaw: One very dry demo
Does the hydrophobic properties of the nanoparticles reduce friction? For instance, would a boat move more quickly through water?
What happens when this gets onto a mucous membrane like your eye?
Thanks for the entertaining talk!
A comment on Talk: Nina Tandon: Could tissue engineering mean personalized medicine?
A comment on Talk: James Stavridis: A Navy Admiral's thoughts on global security
I give credit to the forward thinking of its Supreme Commander Admiral Stavridis, opening lines of communication that foster international dialogue have already proven effective. In the last decade, the Eastern world utilized social networking to end several tyrannical dictatorships, despite their government's futile attempts at censorship.
As Jullen Couvreur mentioned below, communication breeds familiarity, helping to "build trust, integration and tolerance." In this case, communication should ultimately bring peace.
However, I'm certain many countries would be wary that NATO's attempt to set up these lines of communication is to control or monitor them. We desperately need new generations to remove such cynicism from their hearts and make the leap toward a global society rather than a secular one.
A comment on Talk: Neil Harbisson: I listen to color
A reply on Talk: Matt Mills: Image recognition that triggers augmented reality
A reply on Talk: Mina Bissell: Experiments that point to a new understanding of cancer
A reply on Talk: Mina Bissell: Experiments that point to a new understanding of cancer
A comment on Talk: Mina Bissell: Experiments that point to a new understanding of cancer
Scientists certainly do think cancer is a genetic disease. This is backed by a multitude of cellular evidence indicating that most cancer cells demonstrate nuclear/chromosomal abnormalities, abnormal mitoses, and abnormal DNA content. Additionally, carcinogens (like cigarette smoke or viruses) cause genetic mutations in a cell's DNA. This is a problem especially if the mutation affects a proto-oncogene. A "proto-oncogene" is most typically considered a growth or inhibitory pathway in the cell (look up p53 if you're curious). When a carcinogen causes a mutation to these proto-oncogenes they become problematic "oncogenes." Single oncogene mutations probably occur more frequently than we realize, but through cellular feedback mechanisms, they are often told to undergo apoptosis before causing any problems. However, in a fairly famous paper published by Hanahan and Weinberg in Cell (2000; 100: 57-70), there are several established "changes" that must occur in order to establish a viable cancer cell. In no particular order, these are:
1. Self-sufficiency in growth signals
2. Insensitivity to anti-growth signals
3. Evasion of apoptosis
4. Unrestricted replicative potential
5. Sustained angiogenesis
6. Tissue invasion and metastasis
7. Genetic instability
From this talk, I surmise that Dr Bissell research specifically details the importance of "the microenvironment" - or the loss of coherent communication between cells. Therefore, I'm assuming she would place #1 and #2 in the list above as the paramount cause of cancerous growth. In working to reestablish this communication both in the physical (Form) and in the correct relaying of signals (Function), I believe she will push the boundaries of our understanding of cancer. A lifetime's amount of research (and blood, sweat, and tears) is summed up in this talk, for which we should all be humbled.
A comment on Talk: Matt Mills: Image recognition that triggers augmented reality
A reply on Talk: Chris Gerdes: The future race car -- 150mph, and no driver