TED Community » David Maskalick

About Me

CV for David G. Maskalick, PhD
Contact Info:
10106 Deer View Point
Wexford, PA 15090
(724) 935-0507
dmaskal1@yahoo.com

Objective: Seeking research translation, consulting, and teaching opportunities with scientists, engineers, and business persons who need to appreciate how biotechnology and nanotechnology discoveries and inventions can be commercialized to create products that will sustain satisfaction of the demand for the eight basic human needs globally. The eight basic human needs include 1) clean air to breath, 2) clean water to drink, 3) nutritious, palatable food to eat, 4) bio-materials for clothing and housing, 5) bio-fuels for temperature control, transportation and machines, 6) bio-sanitation for waste of people, 7) maintenance of biodiversity, and 8) healthcare. I offer a strong capability to translate research so as to help people understand explanations, evaluate data, employ concepts, coordinate activities, analyze work and develop new ideas.

Education:
1975-1978 BS, Biochemistry, Pennsylvania State University, University Park, P

1979-1984 Ph.D., Biochemistry, Indiana University, Bloomington, IN
Thesis: -Motions and Electrostatic Interactions in Natural and Semisynthetic Myoglobins: A Carbon-13 Nuclear Magnetic Resonance Study- Carbon-13 NMR, semisynthetic incorporation of C-13 labeled amino acids, peptide chemistry, protein purification and analysis. Abstract is attached.

Work Experience:
2002 to 2011 Private Entrepreneur, BiotecConnect, Inc., Wexford, PA

-Vision of BiotecConnect - Sustainably satisfy basic human needs for clean air, clean water, nutritious food, fuel for heat and transportation, materials for clothing and housing, and healthcare.

-Mission of BiotecConnect - Facilitate communication between consumers and producers of discoveries, in biotechnology and nanotechnology, which can be commercialized to satisfy the basic needs of humanity.

-BiotecConnect owned an internet web portal to its relational database to enable knowledge communication in the fields of biotechnology and nanotechnology.

-Knowledge communication will accelerate the development of products that will sustainably fill the global market for basic human needs.

2005 to 2008 Consultant, Proteopure, Pittsburgh, PA
-Contributed ideas to complete product development quickly while recognizing the customer need for a product that performs reproducibly
-Contributed the idea of employing the analysis of designed experiments to discover the factors that must be controlled to maintain reproducible product performance.

1992 to 2000 Research Scientist, Eli Lilly and Company, Indianapolis, IN
-Responsible for and contributed to development of production processes to purify recombinant proteins.
Designed preliminary purification processes based on the biophysical and chemical properties of proteins. Created and developed initial purification processes capable of generating milligrams of high quality product at the lab bench scale using conventional and novel technology. By maximizing the product quality and minimizing the cost of production, a robust purification process was developed in the lab and tested in the pilot plant. Grams of product were manufactured in the pilot plant for activity, analytical, toxicology, and clinical evaluation. Process control was the result of experiments designed to examine factor effects on process outputs such as product quality, yield and reproducibility. Full scale manufacturing facilities were designed based on robust purification processes developed in the lab and tested in the pilot plant.

1984 to 1991 Senior Scientist, Eli Lilly and Company, Indianapolis, IN
-Supervised and contributed to lab and pilot plant scale development of resin separation, batch reaction and filtration protocols.
-Resin separation, batch reactions and filtration operations were the primary methods used to isolate and purify high quality recombinant protein products from fermentation sources. Ion exchange, affinity, reverse phase, size exclusion and hydrophobic interaction modes of resin separation were considered on selected occasions. Resin separation column sizes ranged from one milliliter to several liters in the laboratory and from ten liters to 200 liters in the pilot plant. Chemical modification, protein folding, crystallization and precipitation are types of batch reactions that have been employed using one milliliter to one liter in the laboratory and from ten liters to 5,000 liters in the pilot plant. Ultra-filtration and microfiltration operations ranged from one milliliter to tens of liters in the laboratory and from ten liters to 5,000 liters in the pilot plant. Employed statistically designed experiments for manufacturing process optimization.

-Led and participated in collaboration in groups of scientists, engineers, business experts.

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More About Me

I'm passionate about

Sustaining products to ensure clean air, clean water, food, bio-materials, bio-fuels, bio-waste processing, maintenance of biodiversity, and global access to healthcare using translation of research.

An idea worth spreading

Commercial investment in the biosphere which is our home, planet Earth, will sustain the lives of people and all forms of life globally. If the commercialization of products either directly or indirectly damages the biosphere, planet Earth, our home, then it reduces the survival of people and all forms of life globally. The manufacture, use, and disposal of commercial products must only release into the biosphere chemicals which are part of the biocycle to support life, and must not release toxins to life into the biosphere. Through the end of the 20th century people had only withdrawn capital from the biosphere. In the 21st century people possess the ability to employ biotechnology and nanotechnology research discoveries and inventions to commercialize products that return capital to the biosphere as an investment in the future survival of life on our home planet Earth.

Talk to me about

Using research translation for discussions with business, science and government professionals regarding a sustained supply of food, bio-materials, bio-processing of waste, biodiversity and medicine

People don't know that I'm good at

I can explain research discoveries and inventions so people understand them and recognize the value they hold so as to ensure the sustainable supply of products all people globally need to survive.

My TED Story

Through the end of the 20th century people had only withdrawn capital from the biosphere. In the 21st century people must seize the opportunity to commercialize biotechnology and nanotechnology research discoveries and inventions to make products that return capital to the biosphere thus sustaining survival of life on our home planet Earth. Products that capture all waste before release into the biosphere and convert it into chemicals that are part of the bio-cycle so as to prevent any further pollution of the land we need to grow food, the water we need to drink, and the air we need to breathe return capital to the biosphere. Methods producing a sustainable food supply for all future people, globally, return capital to the biosphere. Bio-fuels and bio-materials which are made using sunlight for energy and carbon, oxygen, nitrogen and hydrogen from the biosphere while returning those elements in the form of chemicals that are part of the biocycle return capital to the biosphere.

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