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When it comes to vaccine intervention for disease control, should personal liberty go before the benefit to society?
This question is extremely important when one considers current news on the Human Papillomavirus vaccine. The main vaccine, Gardasil, has been widely used on women ages 9-26 since its introduction in 2006. The vaccine first made waves in 2007 when Texas governor Rick Perry issued an executive order to mandate the vaccine for all young women in Texas. Even though it was met with much opposition and ultimately failed, the question still remained: should we have a mandatory HPV vaccine for all women? The two sides of the argument clash, each bringing significant evidence to bear on the issue. Mathematical models indicate that with a vaccine as effective as this one (about 100%), mandating the vaccine will stamp out the virus types targeted by the vaccine. HPV is the most common STI with 45% of college age women currently infected. Freeing society of such a dangerous virus, the number one cause of cervical cancer, is a highlight of the pro-mandate argument. The opposition suggests that personal liberty is at stake, and that parents should have the choice to vaccinate their children if they believe the vaccine is worth it for them. What do you think? Is it reasonable to limit personal liberty for the good of the community in the face of a spreading killer virus?














Srdjan Kamenko 50+
Sarah Lange
Richard Johnson
Srdjan Kamenko 50+
Steve Sikora
http://search.mercola.com/search/pages/Results.aspx?k=gardasil
There are dozens of articles at the above listed link. Here are direct links to some of them:
http://articles.mercola.com/sites/articles/archive/2008/10/25/prominent-scientist-warns-of-hpv-vaccine-dangers.aspx
http://articles.mercola.com/sites/articles/archive/2009/08/08/Hundreds-of-Thousands-of-Reactions-to-Gardasil-Is-Your-Child-Next.aspx
http://articles.mercola.com/sites/articles/archive/2009/02/24/spain-withdraws-gardasil-after-illnesses.aspx
http://articles.mercola.com/sites/articles/archive/2010/04/17/time-for-the-truth-about-gardasil.aspx
http://articles.mercola.com/sites/articles/archive/2010/07/20/does-gardasil-actually-increase-your-risk-of-cervical-cancer.aspx
Besides these articles I've linked from Dr. Mercola's site, there are several other internal links within these articles to research, tests and statistics from studies not just in the United States, but in other countries as well, that contradict many of the claims being made in an effort to have this vaccine given.
Please do not follow the herd, as sheep are usually sheared.
Kevin McNaught
Dr. Mercola cites information from the Vaccine Adverse Event Reporting System (VAERS), which is a reputable government agency cosponsored by the FDA and CDC. But, he does not put the information on the adverse effects reported in context. Just because an adverse effect is reported to a particular vaccine, this does not mean that they were caused by the vaccine itself. Investigators do follow up on the adverse reactions, but rarely find any cause-effect relationship.
For example, if I took the Gardasil vaccine, then a few days later died in a fatal car crash, I may be included in the VAERS numbers. Maybe the vaccine did cause me to lose consciousness and swerve off the road, but this is all subject to speculation. People assume that the VAERS reports imply a causality, but this is not the case.
Grant Sutton
HPV is a much less fatal or crippling disease for most people. Requiring everyone to take 3 shots to try to protect against it is within the governments powers but I don't believe they should do so yet. I do believe it is within the realm though of trying to make sure that people who want the shots should be able to get them. This means government could try to reduce the price of the vaccine, and perhaps provide a subsidy for women that cant afford to pay.
Steve Sikora
As a free person on this planet, no government or authority should have the right to do anything to me against my will, as long as I am living my life without compromising the liberties of any other people. Cancer is not a contagious disease, it is developed by one's own body. You cannot catch cancer like a cold. You develop cancer as the final stage of your body being polluted by toxins. There is no vaccine which can ever be made to prevent someone from getting cancer either by their own personal habits or by exposure to chemicals or other toxins which would cause someone to have any type of cancer, let alone cervical cancer.
Follow the money when you want to see the meaning behind anything. The companies making vaccines, Merck in the case of Gardasil, are businesses that rely on sales to make profits to give to their owners and shareholders. To get their vaccines into the market, they pay enormous amounts of money to federal agencies for approval, which then offer government subsidies to have these same drugs given to the public. It is a huge conflict of interest and creates a financial windfall for these companies, as they practically have guaranteed sales of their products by political force.
Gardasil was "fast tracked" and pushed to market before proper testing could be done and the results to girls given this vaccine may not be fully known for years to come. Please educate yourself by checking alternative, independent sources instead of being blindly fed by the salesmen of a product.
http://articles.mercola.com/sites/articles/archive/2010/11/05/gardasil-vaccine-is-a-flop-for-good-reasons.aspx
Kevin McNaught
However, your risks for a particular cancer can be affected by viral infections. When a virus infects a cell, it can mess with cell cycle regulation, DNA-repair mechanisms, telomerase activity, etc. All of these effects push that particular cell in the direction of becoming cancerous.
In the case of HPV, about 93% or even more of all cervical cancers are tied to HPV infection. In fact, "the presence of HPV in virtually all cervical cancers implies the highest worldwide attributable fraction so far reported for a specific cause of any major human cancer."
Source: http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291096-9896%28199909%29189:1%3C12::AID-PATH431%3E3.0.CO;2-F/abstract
This topic is biologically complex, so I understand why it may be confusing.
Saying cancer is not communicable is mostly correct. Analogously, AIDS isn't communicable either. It is the viruses that causes these disease states that are.
Tanu singh
Varun Gadiraju
There are many women out there who choose to abstain until they are married, or at least until they find "someone special". If a woman and her sexual partner are both virgins at the time, and have not engaged in any sexual contact that would have put them at risk for contracting HPV, that woman does not need the vaccination. If there are ANY potential risks or side effects associated with the vaccine, a mandate would have put her at risk for no reason.
Mandating this vaccine is unnecessary. Spreading awareness through our schools and in the community is sufficient to convince people to get vaccinated.
Richard Johnson
Lucy Irons 50+
Comment deleted
Srdjan Kamenko 50+
Sara Bradford
Sarah Lange
I know that it have been mentioned here a few times already, but I agree that education is something that should be expanded upon. Many students have sex education courses and I don't remember hearing much in there about HPV. Also, if people are more educated on a subject, they may be more apt to talk about it and thus, we might be able to reduce some of the stigmas that exist in talking about sex and STIs.
One last thing I'm curious about...the primary vaccine is established as being for women up until the age of 26. What is the reasoning for that upper age limit? As many women are dating over this age, and there is the unfortunately high rate of divorce, what possibilities other than safe sex practices and abstinence are there for this population?
Thanks!
Srdjan Kamenko 50+
• Merck, the manufacturer of Gardasil vaccine offers a patient assistance program for young women, ages 19-26, based on financial eligibility.
• Some private health insurance policies may provide coverage (private insurance clients will need to pay for the vaccine at the time of service and then submit a receipt for reimbursement from their insurance company).
Source: http://www.plannedparenthood.org/ppsworegon/hpv-cervical-cancer-vaccine-29204.htm
As for your question regarding the upper age limit for the vaccine, here is a direct quote from the CDC: "Both vaccines were studied in thousands of people from 9 through 26 years old and found to be safe and effective for these ages. The vaccine is not licensed in the United States for persons over age 26 years, as GARDASIL has not been demonstrated to prevent HPV-related outcomes in a general population of women and men older than 26 years of age".
Source: http://www.cdc.gov/vaccines/vpd-vac/hpv/vac-faqs.htm
It is interesting, Canada offers the same vaccine but their upper age limit for women is 45 as of April of last year. The difference comes from doing more studies with the vaccine up to that age limit.
Source:
http://www.newswire.ca/en/story/796529/health-canada-approves-gardasil-for-women-up-to-age-45
Sarah Lange
edward long 100+
Srdjan Kamenko 50+
http://www.openeducation.net/2009/01/05/abstinence-only-sex-education-statistics-final-nail-in-the-coffin/
HPV can take months or years to show up on a cervical screen, men can't be tested, it can be passed through oral intercourse, and condoms don't fully protect, thus having sex at all exposes you to the risk of contracting the virus. With a virus as prevalent as this one (20 million in the US, 45% of college aged women) the chances that someone will contract it at some point in their sexual career is very high.
Sources:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1477576/?tool=pmcentrez
http://www.cdc.gov/std/hpv/
Therefore, I believe HPV is a threat to society as long as that society continues to have any kind of sex.
edward long 100+
Varun Gadiraju
But there is a substantial, and I mean SUBSTANTIAL, amount of people who actually choose not to have sex until they are married, at which point both husband and wife are losing their virginity for the first time. Quite often, they have not engaged in any other non coital sexual activity that could have resulted in the contraction of HPV either. As long as they are monogamous, HPV is not a threat to them. If there is any potential side effect whatsoever with this vaccine, how can we justify administering it to them? It's all risk, no reward for those individuals.
And again, there is enough people who make this lifestyle choice, which makes this a very relevant concern. For example, I wonder what the occurrence of HPV is at a school like BYU, which has an honor code that calls for its students to be abstinent.
Srdjan Kamenko 50+
Kevin McNaught
Source: http://www.usatoday.com/news/health/2006-12-19-premarital-sex_x.htm
You may say that this means that 5% of the population would not be benefited by the vaccine. However, their partner would have had to been abstinent as well. Just as a thought experiment, if mating is not assortative, then the chance of two people losing their virginity after marriage would be 0.05 x 0.05 = 0.0025 or .25%. So, hypothetically only a quarter of 1% of the population would be in this category. Of course, mating is probably assortative, with virgins more likely marrying virgins, but it is something to think about.
Also, let's not forget about the high divorce rate in the United States. Even if you remained abstinent until marriage, and so did your life partner, you may still divorce and remarry. In addition, even life-long married couples do occasionally cheat on their spouses.
Krisztián Pintér 200+
a human body contains a lot of parts that can be transplanted. one body can save two with kidney failure, one with liver failure, many with skin burns, one with heart failure, several who needs bone parts, bone marrow, blood etc.
so wouldn't it be beneficial to sometimes get all such people together, kidnap a healthy individual, kill him, and transplant all the organs? one life versus 4-5-6 lives.
what is the fundamental problem with that reasoning?
Daniel Svensson
It's a dangerous path to take, as if this is acceptable, then what's acceptable next? Then a 49:51 sacrifice ratio, and in certain situations even more, is acceptable "for the greater good". Another good thing about not vaccinating everyone is that -IF- the vaccine had unforeseen side effects it's good to not have given it to everyone. If the vaccine by accidental side effects reduces the fertility rate, for example, it's good for the community as a whole that not everyone was infected.
I don't see what's wrong with the older reasoning by who to vaccine against things like the H1N1 virus, that we vaccinate people in the risk zone and people in 'public service', such as hospital personnel while the rest of us can take being sick for a few days if we get infected. If we aren't allowed to deal with the virus in a natural manner we will become 'addicted' to vaccine, which we already are, but in the cases of really harmful diseases such as polio, I do think that it's justified to create that addiction. But for a flue, not really, I'd rather be sick a few days than develop a vaccine addiction.
Grant Sutton
I do fundamentally believe in the greater good argument and I think those that do not should have to pay the cost of their position. H1P1 is a much more mild than if you refuse to get a vaccine for measles, as if you enter a hospital with measles have a high likelihood of killing someone that did not have the option to protect themselves.
I have no problem with people refusing to vaccinate themselves or their babies as long as they are willing to pay for the loss of life they inflict on themselves and others.
H1P1 that liability seems low so signing a waiver that you do not care seems reasonable if the price is affordable.
The slippery slope argument of where do we stop seems to be the reverse of what we actually see. We generally don't vaccinate for disease, if we can control the spread from reaching us effectively. If you are traveling to China you get certain preventive measures that you are not required to get staying in the US. Most of the population does not have to pay that cost of either the vaccine or disease later.
The cost of AIDS treatment vs a $400 mandatory vaccine, one patient if paying for the most comprehensive care could cover most a town. A comprehensive vaccination might be able to remove the cost completely and allow humans to spend their time on now more important problems.
Krisztián Pintér 200+
the real question is the following. if there is something that, on average, benefits society, how we make people do it? we convince? we pay? we ask? or we enforce? this is the real question. do we have a gun in the room or not? do we put people in jail, do we kidnap people and tie them up, do we beat someone? that is the solution we choose? in a so called modern, western, free democracy?
Sean Silverstein
Srdjan Kamenko 50+
http://fullspectrumbiology.blogspot.com/2012/03/from-bed-to-streets-look-into-human.html
http://fullspectrumbiology.blogspot.com/2012/03/understanding-vaccines-and-hpv-mandate.html
We have a lot of embedded links which lead to great sources for a lot of the supporting evidence for both arguments.
Lacie Holt
Srdjan Kamenko 50+
Lacie Holt
Sara Bradford
Stephanie Loredo
Molly O'Connor
In a recent NPR article called HPV Vaccine: The Science Behind The Controversy, the writer Richard Knox gives an overview of both sides of the controversy. Knox talks about how recent studies show that by the time girls reach 15 years old, nearly 10% of American girls are infected with HPV. Not to mention that by age 17, that number doubles to nearly 20%.
Knox also interviewed Dr. Diane Harper, a professor at the University of Missouri-Kansas City School of Medicine. Harper is skeptical of the necessity for the vaccine. By Harper's calculations, the tried-and-true method of regular Pap smears is a more effective way to prevent cervical cancer. In the article, Harper says "Pap smear screening is far and away the biggest thing a woman can do to protect herself, to prevent cervical cancer."
I believe both sides have their truths. I do think that this vaccine is expensive and maybe administered at too young of an age. But I also believe the researchers have a point. If we administer this vaccine at a younger age, quite possibly the antibodies in the younger individual may gain better immunity as compared to a older individual.
Overall, this is a choice. A choice that should either be decided by the parents or by the individual themselves.
Kevin McNaught
On the topic of pap smear screening vs. vaccination, one study shows that "the difference in screening coverage rates among countries affects the effectiveness of the vaccination program." The study also says that "the HPV vaccination program is cost-effective in only 46 countries where per capita GDP is high." I believe the USA would fall into the category.
Source: http://www.ncbi.nlm.nih.gov/pubmed/18835313
I believe the main motivation behind vaccinating the girls young is to protect them before they become sexually active, not because of age-related immune system decline (not to say that doesn't help!) Giving a girl a vaccine if she's already infected with that HPV strain has no upside.
Lia Heifetz
Sandra Lozes
Thank you for the information on HPV and the studies cited. Also, I was being kind by not bringing his financial ties into the equation, but I have read about his link to Merck...he's the governor of Texas afterall, not that he is ever in the forefront of anything unless its to help his political aspirations.
I'm having to go without internet presently, so when I have access I'm going to look into the info on Guardasil. I worked in the pharma industry for several years and enjoy perusing the published studies. I will leave it at that! Take care! Thanks again.
Kevin McNaught
Hillary Moatz
Clinton French
Melinda Wheelock
Until the vaccine is proven to be wholly effective (or the rate of infection becomes staggeringly high), I think the government should really seek to inform the public about the risks that HPV poses and strongly recommend that children are vaccinated before sexual activity begins. If people understand what the vaccine offers and the risks that refusing vaccination poses, they can make better choices.
Ashley Bateman
Stephanie Loredo
Lucy Irons 50+
Grant Sutton
Pundits have an advantage of betting against the field, if they are right in the modern market they get jobs being the soothsayers of our communities. Too many are using the fact that science always leaves room for freak occurances to say don't do the societally protective thing. I think when we decide to trust these people we should see how much stake in themselves they are willing to bet their view is right. That way there is a down side to their bad bets.
Just out of curiosity is there any market out there on the HPV vaccine effectiveness in stopping cervical cancer? Briefly check in-trade and didn't find one.
Hillary Moatz
Sean Silverstein
This issue makes me think about the regulations we have on tobacco. As much as some of us may find it disgusting, as well as a health risk to both the smoker and those around him, it is up to the smoker whether or not he wants to smoke. Compare the questions: Should we ban smoking altogether? Should we mandate vaccination? Both questions yield risks whether they are answered yes or no. Are either of them worth limiting the freedoms of the individual?
Srdjan Kamenko 50+
Lia Heifetz
Srdjan Kamenko 50+
Varun Gadiraju
Zane Yamashita-DeSantis
Tanu singh
Varun Gadiraju
I'm going to quote my response to Srdjan.
"There is a substantial, and I mean SUBSTANTIAL, amount of people who actually choose not to have sex until they are married, at which point both husband and wife are losing their virginity for the first time. Quite often, they have not engaged in any other non coital sexual activity that could have resulted in the contraction of HPV either. As long as they are monogamous, HPV is not a threat to them. If there is any potential side effect whatsoever with this vaccine, how can we justify administering it to them? It's all risk, no reward for those individuals.
And again, there is enough people who make this lifestyle choice, which makes this a very relevant concern. For example, I wonder what the occurrence of HPV is at a school like BYU, which has an honor code that calls for its students to be abstinent."
Rishi Patel
This seems like an easier and cheaper option than vaccinating the masses with a relatively expensive vaccine that we don't know all the facts about. Who knows how long Gardasil is effective or all of the potential side effects? It's just too early to mandate such a vaccine, we can educate people, advertise the potential benefits and let people decide. Forcing insurance companies to pay for the vaccine we don't fully understand and also placing the burden of our children dealing with unknown consequences of this vaccine are just unnecessary. Also, HPV rarely leads to an acute onset of cervical cancer, these cancers can be easily prevented during annual check ups.
Another huge aspect to mandated vaccines is we can express our freedom of choice. Although many colleges require a meningitis vaccine, there are multiple cases in which an individual can claim religious views or other factors to a public health official and attend college without the vaccination.
Until we discovered there are no potential biological side effects of the vaccine and that it lasts forever, we cannot mandate such a vaccine, and in the mean time, we are at a struggle with the social concerns surrounding the mandate on a sexually transmitted disease vaccination. If we have choice, we can refuse.
Kevin McNaught
We've seen how abstinence-only education is ineffective at changing the sexual behaviors of the youth, and I believe any education program we provide advocating for less sex amongst the youth will similarly be a failure.
"The research group found that 'participants [in the abstinence-only program] had just as many sexual partners as nonparticipants and had sex at the same median age as nonparticipants.' In other words, abstinence education programs did nothing favorable – the result was the same as if there were no program being offered at all."
Source: http://www.openeducation.net/2009/01/05/abstinence-only-sex-education-statistics-final-nail-in-the-coffin/
Rishi Patel
Last I checked a Pap smear can cost anything from 11 to 300 dollars. Lets find a way to lower this cost, make these tests more accessible, and teach our youth to utilize them. Instead of eradicating a single virus right now, lets also use this opportunity to teach our youth about safe sex so this lesson can extend to other STD's.
Srdjan Kamenko 50+
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1477576/?tool=pmcentrez
This, combined with the fact that men can't be tested means that if anyone wishes to engage in sexual intercourse at all, they will still have the risk of getting the virus. Wearing condoms also reduces the risk of contraction, however it can be spread from contact by other genital areas uncovered. Abstinence is the only way to decrease the risk to 0%. Unfortunately for HPV there is no such thing as safe sex.
Daniel Svensson
Edit: And I'm not taking stance of whether a vaccine is good or not, merely on the topic about using force or making it illegal to refuse vaccine. The solution is quite obvious to me: use communication, not force.
Grant Sutton
If the choice largely only affects you and you want to increase your chance of dying I do not think it should be mandated, but maybe the government should get you to sign a waiver that if you get cervical cancer it's on your own budget(in the US HMO's and medicare and medicad not required to cover your treatment.)
If the choice affects others because of a large enough population can not protect themselves, then I think some degree of government direct control is beneficial and trumps the rights of the individuals to refuse. Banning travel made sense between black death infected towns, and the government is empowered with the right to take measures that sometimes seem draconian. Typhoid Mary was locked up in a mental hospital, to remove her and protect society from her even though she had done no crime.
I believe that if people make free choices to get sick, when a cheaper preventive measure is easily and readily within their grasp and understood, they should bare part or all of the economic burden. We as a society should try to make cheap effective medical care available to as many people as possible as well. To often we think that we can make a bad choice and face limited or no consequences for that choice. To protect the poor, I think we should pass a law giving free access to anybody below the poverty line to get vaccinated.
Verble Gherulous 20+
The reason why governor Perry made it mandatory was for political favors for himself, his chief of staff, and the Republican party in general. He had absolutely no concern for the science or for the overall health of women. This was so that Merck would have aincome source, nothing more.
That's the social side of the issue, but U will defer to more knoledgeable people on the science/health issue.
Kevin McNaught
"The presence of HPV in virtually all cervical cancers implies the highest worldwide attributable fraction so far reported for a specific cause of any major human cancer."
Source: http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291096-9896%28199909%29189:1%3C12::AID-PATH431%3E3.0.CO;2-F/abstract
Clinton French
Also, the proposal that it be mandated for women is based on the fact that HPV causes a huge risk for cervical cancer, which men cannot get (for obvious reasons). People ask why not make males get it too, but I ask why not mandate it for all women. If a lot men get the vaccine and women still get HPV, then it doesn't help reduce cervical cancer risks, right? And therefore vaccination is less useful if the non-vaccinated women still get HPV and subsequently cervical cancer , right?
Srdjan Kamenko 50+
Source: http://www.cdc.gov/std/hpv/STDFact-HPV-and-men.htm
We can think of a situation in which both men and women get vaccinated, that way the woman are protected against cervical cancer while the men are 1) stopped from giving it to them (for the most part) 2) protected against the majority of genital warts types.
Boki Zelen
Kevin McNaught
Men can experience genital warts, as well as anal, throat, and penile cancer from HPV infection.
Source: http://www.cdc.gov/std/hpv/stdfact-hpv-and-men.htm
Part of the motivation behind the CDC recommendation for vaccinating men was that so few women, less than 1/3, had been vaccinated and that it would aid in halting spread of the infection to females.
Source: http://www.aafp.org/online/en/home/publications/news/news-now/health-of-the-public/20111026acip-hpv-hepb.html
Ross Massimiano